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BI 340 Bethune Cookman University CH8 Genome Structure and Function Questions

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  1. [5] What must be considered when examining an organisms genetic composition? (think, genome size, gene density, genome composition) (MLO 3.1
  2. [7] Explain the roles of the SMCs cohesin and condensin. What are possible outcomes if: a) cohesin is mutated and b) if condensin is mutated (describe any mutation you choose, then explain its effect) (MLO 3.2)
  3. [7] Describe five major types of histone proteins, and explain their roles within the nucleosome. Which histone protein(s) do you think might be the most evolutionarily conserved? Least conserved? Why? (MLO 3.3)
  4. [7] What are the “tails” of the histone proteins, and why are they important? (MLO 3.3)
  5. [4] What is the functional significance of the interaction of proteins containing bromodomains and chromodomains with acetyl transferases or with methylating enzymes? (MLO 3)