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BIO Unfolded Proteins in the Endoplasmic Reticulum Question

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Some diseases are caused by too many unfolded proteins in the endoplasmic reticulum (ER). Which of the following might be a potential therapeutic strategy?

Group of answer choices

Increasing glucosidase II in the ER lumen.

Increasing UDP-glucose in the ER lumen.

Decreasing calnexin in the ER.

Increasing ER mannosidase in the ER lumen.