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Transcriptome of Acute Myelogenous Leukemia Cells Question

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Which of the following would be the MOST useful drug for treating acute myelogenous leukemia?

A drug that makes the proteome of acute myelogenous leukemia cells resemble the proteome of differentiated neutrophils.

A drug that makes the transcriptome of acute myelogenous leukemia cells resemble the transcriptome of differentiated neutrophils.

A drug that makes the RNA splicing of acute myelogenous leukemia cells resemble the RNA splicing of differentiated neutrophils.

A drug that makes the histone code of acute myelogenous leukemia cells resemble the histone code of differentiated neutrophils.